射电天文研究组知识库

目的 初步探讨日冕物质抛射(CME)引起地磁场变化对稳定型心绞痛患者血液流变学的影响。方法选取2014年因胸闷、胸痛在昆明医科大学第一附属医院心脏内科住院的患者162例,根据冠心病诊断标准,将其分为稳定型心绞痛组(85例)和无冠心病组(77例)。在未给予任何药物前提下,检测患者低剪切力全血黏度(1.00s-1)、高剪切力全血黏度(200.00s-1)和血浆黏度。联合云南省天文台记录2014年云南的地磁活动情况,地磁指数Dst≤-30nT为地磁宁静,Dst>-30nT为地磁活动。分析两组地磁宁静期和地磁活动期血液流变学指标的变化情况,并采用多元线性回归分析血液流变学指标的影响因素。结果 2014年共34d地磁活动,平均年发生率为9.3%。无冠心病组地磁活动时低剪切力全血黏度和高剪切力全血黏度均高于地磁宁静时(P<0.05);无冠心病组地磁宁静和地磁活动时血浆黏度比较,差异无统计学意义(P>0.05)。稳定型心绞痛组地磁活动时低剪切力全血黏度、高剪切力全血黏度高于地磁宁静时(P<0.05);稳定型心绞痛组地磁宁静和地磁活动时血浆黏度比较,差异均无统计学意义(P>0.05)。多元线性回归分析结果显示,高血脂、地磁情况是低剪切力全血黏度和高剪切力全血黏度的影响因素(P<0.05);高血脂是血浆黏度的影响因素(P<0.05)。结论 无论生理或病理状态下,CME引起地磁场变化可导致机体血液黏度升高。

Objective To explore the influence of geomagnetic activity caused by coronal mass ejections (CME) on hemorheology in patients with stable angina. Methods We enrolled 162 cases who received inpatient treatment in Department of Cardiology, the First Affiliated Hospital of kunming Medical University due to chest tightness and chest pain in 2014.According to the coronary heart disease diagnosis standard, they were divided into stable angina group (85 cases) and non-CHD group (77cases). Hemodynamic indexes including low-shear whole blood viscosity (1.00s^-1), high-shear whole blood viscosity (200.00s^-1) and plasma viscosity were measured in both groups before receiving any drug treatment. Based on the geomagnetic activity in Yunnan Province in 2014 monitored by Yunnan Observatories, Chinese Academy of Sciences, we defined the period with Dst≤-30nT as geomagnetic quiet period, and the period with Dst＞-30nT as geomagnetic active period. The variations of hemodynamic indexes in geomagnetic quiet and active periods were compared using the paired test. And the associated factors of hemorheology were investigated by multiple linear regression analysis. Results Geomagnetic activity occurred in 34 days in 2014 , with an average annual incidence of 9.3％. In non-CHD group, both the low-shear and high-shear whole blood viscosity levels were higher in the geomagnetic active period than in the geomagnetic quiet period (p＜0.05), while the plasma viscosity level changed little (P＞0.05). In stable angina group, the low –shear and high-shear whole blood viscosity levels were higher in the geomagnetic active period than in the geomagnetic quiet (P＜0.05), but the plasma viscosity level varied little (P＞0.05) . Multiple linear regression analysis showed that hyperlipidemia and geomagnetic activity had significant effect on low-shear and high-shear whole blood viscosity (P＜0.05). conclusion  Changes in geomagnetic field due to CME can lead to elevated blood viscosity in physiological or pathological conditions.